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KMID : 1234520070020010078
Korean Journal of Urogenital Tract Infection Inflammation
2007 Volume.2 No. 1 p.78 ~ p.82
Clinical Characteristics of Eosinophilic Cystitis in Adults: According to the Cystoscopic Findings
Jeon Joon-Seong

Cho In-Rae
Abstract
Purpose: Eosinophilic cystitis is a rare disease, which was reported 15 cases in Korea. We describe our clinical experience with eosinophilic cystitis patients who were confirmed in pathology.

Materials and Methods: Six men and two women were diagnosed with eosinophilic cystitis between 2000 and 2006. Mean patient age at presentation was 71 years (range 62 to 82). A retrospective chart review was performed to assess clinical presentations, diagnosis, treatment and outcomes.

Results: 6 patients (75%) presented with combination of gross hematuria and irritative bladder symptoms. 1 patient had acute urinary retention and 1 patient was asymptomatic. Allergic diseases (asthma, allergic contact dermatitis) were present in 2 patients. The remaining 6 patients were associated with urologic disorders (BPH, bladder carcinoma, bladder stone, etc). Laboratory data include peripheral eosinophilia in 3 of 7 (43%), hematuria in all 8, pyuria in 4 of 8 (50%), positive urine culture 2 of 8 (25%). Cystoscopy showed erythema in all cases and tumor-like lesions or edema in 6 (85%). Transurethral resection of the bladder lesion was performed in 2 cases. All patients received antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids and experienced the marked improvement during a follow-up duration.

Conclusion: Eosinophilic cystitis is more common in male than female. Most common presenting symptomswere hematuria and irritating bladder symptoms. Resection of the bladder lesion with systemic treatment of corticosteroids, NSAIDs and antibiotics showed good results.
KEYWORD
Bladder, Cystitis, Eosinophils
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